Identifying the Microbiomic Basis of Disease

Human genetic and metabolic diversity is heavily influenced by complex microbial communities that inhabit the human body. The microbiota is highly variable both within and between people in body habitats such as the gut, skin, and oral cavity, and changes in the microbiota can cause or prevent disease. In this talk, we discuss the biological problem of comparing microbial communities across people, body habitats, health conditions, and time, along with the related computational problems of designing taxonomically universal PCR primers, determining and quantifying the composition of environmental samples, and comparing abundance profiles across microbial communities.

Информация о лекции с сайта RECOMB Satellite Conference on Bioinformatics Education