From Sequence to Structure and Function: Inspiring Students with Bioinformatics Problems

Recent advances in sequencing technology have enabled scientists to gather large amounts of DNA and RNA sequence data. One of the bioinformatics challenges is extracting new insights about the structure and function of biomolecules from the wealth of sequence data. In this talk, we look at two problems in the field of computational molecular biology designed to stimulate and challenge students. The first problem relates to understanding the secondary structure of an RNA molecule based on its primary sequence. The second problem relates to processing large amounts of DNA sequence data so as to capture the internal structure in the data and support a range of queries on the data efficiently. Applications will be discussed for aligning high-throughput sequencing reads to a genome and for screening a genome for interesting genetic elements such as CRISPRs.

Информация о лекции с сайта RECOMB Satellite Conference on Bioinformatics Education